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Fig. 5
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- ZDB-FIG-150928-4
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- Chen et al., 2015 - Invasiveness and metastasis of retinoblastoma in an orthotopic zebrafish tumor model
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Fig. 5
Vegf-aa morpholino treatment attenuates retinoblastoma metastasis. (a) Vegf-aa specific morpholinos and control morpholinos were injected into the yolk of each embryo at the 1-2 cell stage. DiI-labeled SJmRBL-8 retinoblastoma cells were intravitreally implanted in zebrafish at 48 hpf. Retinoblastoma invasion and metastasis were monitored at day 0 and day 4 post-implantation. Arrows point to metastatic tumor cells. Bar = 100 µm. (b) Quantification of metastatic tumor cells and the averages of maximal distance of metastatic foci in Vegf-aa and control morpholinos-treated zebrafish embryos (n = 20 embryos/group). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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