ZFIN Figure: Chen et al., 2015, Fig. 2

ZFIN ID: ZDB-FIG-150827-16

ZFIN ID: ZDB-FIG-150827-16

Chen et al., 2015 - Expression change in Angiopoietin-1 underlies change in relative brain size in fish. Proceedings. Biological sciences 282(1810) Full text @ Proc. Biol. Sci.

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	mi2Tg + MO1-angpt1
Knockdown Reagent:	MO1-angpt1
Observed In:	brain
Stage:	Day 4

Fig. 2

Brain morphology of zebrafish Ang-1 morphant. (a) Knockdown of Ang-1 expression caused the small-sized brain and the reduction of GFP intensity in the Ang-1 morphant (Ang-1 MO) compared with the control group (ctrlMO) in the Tg (alpha-tubulin-GFP) background line at 4 dpf (n = 6). Dashed lines illustrate the brain area. (b) Ang-1 MO shows the significantly smaller relative brain diameter (controlled for body size) than the control and rescue group (ANCOVA: group: F_2,62 = 74.55, p < 0.001, body length: F_1,62 = 14.47, p < 0.001; post hoc pairwise group comparisons: ctrlMO versus Ang-1 MO: p < 0.001, ctrlMO versus Ang-1 rescue: p = 0.069, Ang-1 MO versus Ang-1 rescue: p < 0.001; ***p < 0.001).

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
mi2Tg + MO1-angpt1	standard conditions	Day 4	brain decreased size, abnormal

Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Biol. Sci.