ZFIN Figure: Hao et al., 2015, Fig. 4

ZFIN ID: ZDB-FIG-150408-8

ZFIN ID: ZDB-FIG-150408-8

Hao et al., 2015 - Motoneuron development influences dorsal root ganglia survival and Schwann cell development in a vertebrate model of spinal muscular atrophy. Human molecular genetics 24(2):346-60 Full text @ Hum. Mol. Genet.

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Gene:	EGFP
Fish:	os26Tg smn1^fh229/fh229; os26Tg smn1^fh229/fh229; os26Tg; os44Tg
Anatomical Terms:	motor neuron axon motor neuron cell body
Stage:	Prim-5

PHENOTYPE:

Fish:	smn1^fh229/fh229 smn1^fh229/fh229; os26Tg smn1^fh229/fh229; os26Tg; os44Tg smn1^fh229/fh229; os44Tg
Observed In:	motor neuron motor neuron axon
Stage Range:	Prim-5 to Long-pec

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Fish	Conditions	Stage	Anatomy	Assay
EGFP	os26Tg	standard conditions	Prim-5	motor neuron axon	IFL
			Prim-5	motor neuron cell body	IFL
	smn1^fh229/fh229; os26Tg	standard conditions	Prim-5	motor neuron axon	IFL
			Prim-5	motor neuron cell body	IFL
	smn1^fh229/fh229; os26Tg; os44Tg	standard conditions	Prim-5	motor neuron axon	IFL
			Prim-5	motor neuron cell body	IFL

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
smn1^fh229/fh229	standard conditions	Long-pec	motor neuron axon decreased branchiness, abnormal
		Long-pec	motor neuron morphology, abnormal
smn1^fh229/fh229; os26Tg	standard conditions	Prim-5	motor neuron axon morphology, abnormal
		Prim-5	motor neuron morphology, abnormal
smn1^fh229/fh229; os26Tg; os44Tg	standard conditions	Prim-5	motor neuron axon morphology, normal
		Prim-5	motor neuron morphology, normal
smn1^fh229/fh229; os44Tg	standard conditions	Long-pec	motor neuron axon branchiness, normal
		Long-pec	motor neuron axon morphology, normal

Full text @ Hum. Mol. Genet.