Fig. S17
- ID
- ZDB-FIG-150311-47
- Publication
- Lin et al., 2014 - Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling
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Expression of p66β and mycbp in zebrafish disrupts Hedgehog (Hh) signaling and results in somite defects. (A) Lateral view of chevron-shaped somites in wild-type zebrafish embryos at 24 hours postfertilization (hpf). (B) Zebrafish embryos injected with p66β exhibited U-shaped somites, consistent with disruption of Hh signaling. (C) Zebrafish embryos injected with mycbp also displayed U-shaped somites, known to be associated with disruption of Hh signaling. Reduced or increased Hh signaling can both produce U-shaped somites. |