FIGURE

Fig. 1

ID

ZDB-FIG-141024-2

Publication

Zdebik et al., 2013 - Epilepsy in kcnj10 Morphant Zebrafish Assessed with a Novel Method for Long-Term EEG Recordings

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Fig. 1

Invasive recordings using a patch pipette inserted into the optic tectum of 120 hpf old ZF larvae.

(A), 22 min recording of a buffer-injected control larva. Frequent spiking and also low level activity is present throughout the trace. (B), higher temporal and voltage resolution of the area marked in A. (C), kcnj10a morphant larva, showing genuine epileptic activity (marked with stars). Low-level activity is followed by a spontaneous large transient (arrowhead). Similar transients were seen while the fish showed brief total body contractions and could also be produced by a light tap on the recording setup (vertical arrow). The square marked “D” in C is shown in (D) at higher resolution.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TL + MO1-kcnj10a TL + MO2-kcnj10a
Knockdown Reagents:	MO1-kcnj10a MO2-kcnj10a
Observed In:	whole organism
Stage:	Day 5

Phenotype Detail

Acknowledgments

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