FIGURE

Fig. 5

ID

ZDB-FIG-140919-10

Publication

Pi-Roig et al., 2014 - Distinct tissue-specific requirements for the zebrafish tbx5 genes during heart, retina and pectoral fin development

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Fig. 5

tbx5b knock-down causes a delay in pectoral fin growth. (a,i,q) Pectoral fin morphology at 3 dpf. Dorsal views are shown with anterior to the top. (b-h) Expression of the developing pectoral fin markers in control (ctrl) MO-injected embryos. (c′-h′) Higher magnifications of (c-h). (j-p) Pectoral fin markers expression in tbx5b-morphant embryos. (k′-p′) Higher magnifications of (k-p). (r,s) tbx5a morphants. (t) Model for the differential requirements for the tbx5 genes during pectoral fin development. b-h, j-p,r,s are dorsal views with anterior to the left. c′-h′,k′-p′ are lateral views with anterior to the left.

Expression Data

Genes:	etv4 fgf10a fgf24 tbx5a
Fish:	WT WT + MO1-tbx5b
Knockdown Reagent:	MO1-tbx5b
Anatomical Terms:	mesenchyme pectoral fin mesoderm pectoral fin bud pectoral fin ectoderm pectoral fin bud ectoderm
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-tbx5a WT + MO1-tbx5b
Knockdown Reagents:	MO1-tbx5a MO1-tbx5b
Observed In:	pectoral fin pectoral fin development
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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