FIGURE

Fig. S14

ID

ZDB-FIG-140910-11

Publication

Pfefferli et al., 2014 - Specific NuRD components are required for fin regeneration in zebrafish

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Fig. S14

Hdac1 inhibition after blastema formation is sufficient to block reactivation of osteocalcin expression.

(A) Caudal fins of osteocalcin:GFP transgenic fish at 3 dpa and 7 dpa treated with DMSO or MGCD0103 starting at 3 dpa. osteocalcin:GFP expression was not reactivated in fin regenerates treated with MGCD0103 after blastema has been formed. (B) Uninjured caudal fins of osteocalcin:GFP transgenic fish before and 10 days after MGCD0103 treatment. MGCD0103 treatment does not alter osteocalcin:GFP expression in uninjured fins. Constant exposure times were used. Scale bars: 100 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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