FIGURE

Fig. S4

ID
ZDB-FIG-140807-17
Publication
Burger et al., 2014 - A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12
Other Figures
All Figure Page
Back to All Figure Page
Fig. S4

(A) 8 dpf old twwh:HRAS embryos treated with 1% DMSO (control) show the typical tumor phenotype. (B) 8 dpf old twwh:HRAS embryos treated with 15 µM LY294002 with slightly reduced tumor load; however, this effect was inconsistent and LY294002 treatment did not result in improved survival (data not shown). (C) 8 dpf old twwh:HRAS embryos treated with 10 µM bpV(HOpic). The observed tumor load was similar to that in control fish.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.