FIGURE

Fig. 7

ID
ZDB-FIG-140805-5
Publication
Bonetti et al., 2014 - Distinct and Overlapping Functions of ptpn11 Genes in Zebrafish Development
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Fig. 7

Impaired Erk/MAPK, but not Akt/PKB signalling in Shp2 double mutant embryos.

WT, ptpn11a-/-, ptpn11b-/- and ptpn11a-/- ptpn11b-/- embryos were lyzed and immunoblotted with phosho-specific antibody for ERK and AKT; membranes were then reprobed for total Erk and Akt expression to control for loading. The blots were quantified and the ratio of phosphorylated protein/total protein from three independent experiments is indicated below each lane.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Day 5

Phenotype Detail
Acknowledgments
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