ZFIN ID: ZDB-FIG-140701-5
Aigler et al., 2014 - Selection and constraint underlie irreversibility of tooth loss in cypriniform fishes. Proceedings of the National Academy of Sciences of the United States of America   111(21):7707-12 Full text @ Proc. Natl. Acad. Sci. USA
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage Range: Pec-fin to Protruding-mouth
PHENOTYPE:
Fish:
Observed In:
Stage: Days 7-13

Fig. 3

Ectopic Eda expression restores upper pharyngeal teeth to the zebrafish. Lower pharyngeal teeth (arrows) in lateral (A) and transverse (B) views of wild-type alizarin red-stained larvae. (C and D) bmp2b expression is limited to tooth germs (arrows) of the lower pharynx in wild-type. Upper pharyngeal teeth (arrowheads) in lateral (E) and transverse (F) views of ef1α:eda transgenic zebrafish. (G) bmp2b expression is induced in the upper pharyngeal epithelium (arrowhead) by ectopic eda expression and becomes limited to tooth germs (arrowhead) at later stages (H). Abbreviations: cb5, fifth ceratobranchial; cl, cleithrum; cp, chewing pad; d, dentary bone; n, notochord; y, yolk. (Scale bars, 50 μm.)

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
bmp2b WT standard conditions Pec-fin tooth placode ISH
Protruding-mouth tooth placode ISH
cs1Tg; cs3Tg standard conditions Pec-fin tooth placode ISH
Protruding-mouth tooth placode ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
cs1Tg; cs3Tg standard conditions Days 7-13 ceratobranchial 5 tooth increased amount, abnormal
Days 7-13 ceratobranchial 5 tooth mislocalised, abnormal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA