FIGURE

Fig. 4

ID

ZDB-FIG-131210-18

Publication

Sheehan-Rooney et al., 2013 - Ahsa1 and Hsp90 activity confers more severe craniofacial phenotypes in a zebrafish model of hypoparathyroidism, sensorineural deafness and renal dysplasia (HDR)

Other Figures

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Fig. 4

Graded injection of gata3 morpholino recapitulates the background-specific gata3 mutant phenotypes. (A,A2) Uninjected (UIC) embryos have normal neurocrania and trabeculae. (B,B2) Injection of 5 ng gata3 morpholino results in the lateral commissure attaching to the trabeculae (arrow, B) and improper stacking of cells within the trabeculae (arrowheads, B2). (C,C2) Injection of 15 ng of gata3 morpholino causes trabeculae loss. (D) Quantification of the average number of trabeculae/embryo.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-gata3
Knockdown Reagent:	MO1-gata3
Observed In:	embryonic neurocranium morphogenesis neurocranial trabecula neurocranial trabecula chondrocyte neurocranium
Stage:	Day 5

Phenotype Detail

Acknowledgments

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