FIGURE

Fig. S3

ID

ZDB-FIG-130508-3

Publication

Poulain et al., 2013 - Proteoglycan-mediated axon degeneration corrects pretarget topographic sorting errors

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Fig. S3

Neuronal activity in RGCs is not required for correction of missorted ON axons (related to Figure 2).
(A-B′) ON (A, B; blue in A′, B′) and VN (red in A′, B′) axons are properly sorted at 72 hpf in mao mutant that lacks neuronal activity in RGCs, Lateral views, confocal maximal projections. (C-D) Measurement of axon sorting in the tract in mao mutant (C) and sibling (D). Intensities of DiD and Oil signals were plotted along a reference line perpendicular to the tract as indicated in A′. Profiles shown as examples reveal that DiD and Oil signa ls do not overlap at 72 hpf. Missorting indexes (MI) are similar between mao mutants and siblings and indicate that ON axons have been properly sorted in the absence of neuronal activity in RGCs.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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