FIGURE

Fig. S6

ID

ZDB-FIG-130429-47

Publication

Hegarty et al., 2013 - UBIAD1-mediated vitamin K2 synthesis is required for vascular endothelial cell survival and development

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Fig. S6

Endothelial survival is compromised in reh mutants owing to increased apoptosis by 36 hpf. (A-D) Confocal projections of Tg(kdrl:gfp) wild-type (wt) and reh mutant zebrafish that were TUNEL stained (red) reveal that (D) reh endothelial cells exhibit increased apoptosis at 36 hpf when compared with (C) wild-type endothelial cells. However, there appeared to be no significant difference in endothelial cell death between (A) wild-type and (B) reh embryos at 28 hpf. (E,F) The number of apoptotic cells observed per high-power field for each condition. Mean+s.e.m. Student’s t-test, *P<0.1 (n=15 reh and wild-type zebrafish).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ubiad1^s587a/s587a; s843Tg
Observed In:	blood vessel endothelial cell apoptotic process
Stage:	Prim-25

Phenotype Detail

Acknowledgments

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