FIGURE

Fig. 3

ID

ZDB-FIG-130425-19

Publication

Drerup et al., 2013 - JNK-Interacting Protein 3 Mediates the Retrograde Transport of Activated c-Jun N-Terminal Kinase and Lysosomes

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Fig. 3

pJNK levels were elevated in jip3nl7 axon terminals.

(A–H) Immunolabeling for active JNK (pJNK; red in merge; white in single channel) in proximal (NM1) and distal (NM3) neuromasts at 2 and 5 dpf. pJnk levels were elevated in all axon terminals in jip3^nl7 mutants (A–I; arrowheads). (I,J) Mean fluorescent intensity (background subtracted; see Materials and Methods for details) of pJNK and total JNK (tJNK) labeling in NM1 axon terminals and the pLL ganglion (pLLg) at 5 dpf. (ANOVA, post-hoc contrasts; *-p<0.001). Scale bars = 10 μm.

Expression Data

Gene:	EGFP
Antibody:	Ab15-mapk
Fish:	nl1Tg mapk8ip3^nl7/nl7; nl1Tg
Anatomical Terms:	posterior lateral line axon posterior lateral line axon terminus
Stage Range:	Long-pec to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mapk8ip3^nl7/nl7; nl1Tg
Observed In:	posterior lateral line axon terminus regulation of JNK cascade
Stage Range:	Long-pec to Day 5

Phenotype Detail

Acknowledgments

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