ZFIN Figure: Porazzi et al., 2012, Fig. 3

ZFIN ID: ZDB-FIG-130315-16

ZFIN ID: ZDB-FIG-130315-16

Porazzi et al., 2012 - Disruptions of Global and Jagged1-Mediated Notch Signaling Affect Thyroid Morphogenesis in the Zebrafish. Endocrinology 153(11):5645-5658 Full text @ Endocrinology

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Genes:	EGFP kdrl tg
Fish:	WT mib1^ta52b/ta52b s843Tg
Condition:	chemical treatment: DAPT
Anatomical Terms:	pharyngeal vasculature blood vessel endothelium thyroid follicle thyroid primordium
Stage Range:	Long-pec to Protruding-mouth

PHENOTYPE:

Fish:	mib1^ta52b/ta52b s843Tg
Condition:	chemical treatment: DAPT
Observed In:	pharyngeal vasculature thyroid gland development thyroid primordium
Stage Range:	Long-pec to Protruding-mouth

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Fish	Conditions	Stage	Anatomy	Assay
EGFP	s843Tg	control	Long-pec	pharyngeal vasculature blood vessel endothelium	IFL
			Protruding-mouth	pharyngeal vasculature blood vessel endothelium	IFL
	s843Tg	chemical treatment: DAPT	Long-pec	pharyngeal vasculature blood vessel endothelium	IFL
			Protruding-mouth	pharyngeal vasculature blood vessel endothelium	IFL
kdrl	WT	control	Long-pec	pharyngeal vasculature blood vessel endothelium	ISH
			Protruding-mouth	pharyngeal vasculature blood vessel endothelium	ISH
	WT	chemical treatment: DAPT	Long-pec	pharyngeal vasculature blood vessel endothelium	ISH
			Protruding-mouth	pharyngeal vasculature blood vessel endothelium	ISH
	mib1^ta52b/ta52b	control	Long-pec	pharyngeal vasculature blood vessel endothelium	ISH
			Protruding-mouth	pharyngeal vasculature blood vessel endothelium	ISH
tg	WT	control	Long-pec	thyroid primordium	ISH
			Protruding-mouth	thyroid follicle	ISH
	WT	chemical treatment: DAPT	Long-pec	thyroid primordium	ISH
			Protruding-mouth	thyroid follicle	ISH
	mib1^ta52b/ta52b	control	Long-pec	thyroid primordium	ISH
			Protruding-mouth	thyroid follicle	ISH

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
mib1^ta52b/ta52b	control	Protruding-mouth	pharyngeal vasculature separated from thyroid primordium, abnormal
		Protruding-mouth	thyroid primordium mislocalised ventrally, abnormal
s843Tg	chemical treatment: DAPT	Long-pec	pharyngeal vasculature disorganized, abnormal
		Protruding-mouth	pharyngeal vasculature disorganized, abnormal
		Protruding-mouth	thyroid gland development decreased process quality, abnormal
		Protruding-mouth	thyroid primordium malformed, abnormal

Full text @ Endocrinology