FIGURE

Fig. 5

ID

ZDB-FIG-120301-33

Publication

Ghotra et al., 2012 - Automated whole animal bio-imaging assay for human cancer dissemination

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Characterization of tumor cell foci identified by macro using high-resolution imaging.

(A) Quantification of the mean diameter of macro-identified tumor cell foci from the tail region of PC3-injected embryos. Data obtained from 5 embryos. (B) High resolution imaging of CM-DiI-labeled PC3 tumor cell foci. (B1) Macro-identified PC3 tumor cell foci. (B2) Zoom-in on area indicated in B1 shows tumor cells in association with host vasculature. (B3 and B4) Three dimensional reconstruction and surface rendering of area in insert of B2; arrowheads point to tumor cell partly inside distal longitudinal anastomotic vessel (Video S2 and S3). (C) High resolution imaging of PC3-mCherry tumor cell foci. C1–4, as B1–4 for PC3-mCherry. Scale bar is 100 µm in B1 and C1; 50 μm in B2 and C2; 15 μm in B3 and C3; 10 μm in insets in B3 and C3; 5 μm in B4 and C4.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One