ZFIN ID: ZDB-FIG-110125-6
Vettori et al., 2011 - Developmental defects and neuromuscular alterations due to mitofusin 2 gene (MFN2) silencing in zebrafish: A new model for Charcot-Marie-Tooth type 2A neuropathy. Neuromuscular disorders : NMD   21(1):58-67 Full text @ Neuromuscul. Disord.
Knockdown Reagent:
Observed In:
Stage: Long-pec

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
ml2Tg + MO1-mfn2 standard conditions Long-pec CaP motoneuron branchiness, abnormal
Long-pec CaP motoneuron disorganized, abnormal
Long-pec neuromuscular junction development disrupted, abnormal
Long-pec RoP motor neuron decreased length, abnormal
Long-pec RoP motor neuron immature, abnormal
Long-pec skeletal muscle acetylcholine-gated channel clustering disrupted, abnormal
Full text @ Neuromuscul. Disord.