FIGURE
Fig. 6
Fig. 6
HMG-EnR constructs mimic the effects of WT Sox3 on organizer markers. All embryos are 4.5 hpf, animal pole view, dorsal right. Sox3HMG-EnR (C), but not Sox3HMG-VP16 (B), repressed all markers (boz, sqt, chd, gsc), as compared with controls (A). Similarly, Sox3HMG-EnR (F), but not Sox3HMG-VP16 (E), inhibited the activation of these markers by S37A β-catenin 2 (D). Scale bar: ∼200 μm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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