FIGURE

Fig. 1

ID

ZDB-FIG-100519-1

Publication

Ng et al., 2002 - The limb identity gene Tbx5 promotes limb initiation by interacting with Wnt2b and Fgf10

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Fig. 1

Zebrafish tbx5 is required for pectoral fin initiation and outgrowth. All panels show the dorsal view of zebrafish embryos with anterior to the top. (A-E) Five dpf zebrafish embryos injected with control (A,C) or tbx5 (B,D,E) morpholinos. Embryos with 10 ng of tbx5 morpholino lack pectoral fins (B, asterisk) and Alcian Blue cartilage staining (E, asterisk), unlike control-injected embryos (A,C, arrows). Injection of a lower dose (2 ng, as in D) results in a milder fin phenotype such as a reduced pectoral fin blade (arrow in D).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO3-tbx5a
Knockdown Reagent:	MO3-tbx5a
Observed In:	pectoral fin pectoral fin lepidotrichium pectoral girdle
Stage:	Day 5

Phenotype Detail

Acknowledgments

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