Fig. 5
- ID
- ZDB-FIG-100504-17
- Publication
- Tay et al., 2010 - A vertebrate-specific Chp-PAK-PIX pathway maintains E-cadherin at adherens junctions during zebrafish epiboly
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Localization of β-cat at the AJs requires Chp signaling. (A) A middle sagittal plane of the embryo at 60% epiboly immunostained with β-cat is also derived from the Z stack. β-cat was no longer maintained at the AJs in the EVL and was found predominately in cytoplasm. Scale bars represent 20 μm. (B) Immunostaining of β-cat comparing the EVL and DEL of un–injected control and Chp morphant. Levels of anti-β-cat staining at AJs were severely reduced in Chp morphants. The delocalized β-cat protein was detected within intracellular structures, but no nuclear enrichment was observed relative to controls. |
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Stage: | Shield |
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Stage: | Shield |