FIGURE

Fig. 3

ID

ZDB-FIG-091215-3

Publication

Yanicostas et al., 2009 - Anosmin-1a is required for fasciculation and terminal targeting of olfactory sensory neuron axons in the zebrafish olfactory system

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Fig. 3

Effects of anosmin-1a depletion can be rescued by ectopic expression of the protein. Frontal views of 48 hpf omp-tau;;GFP embryos injected with mis-matching control kal1a MO (A), MO kal1a-insensitive kal1a RNA (B), MO kal1a (C) or omp-tau;;GFP kal1a morphant co-injected with MO kal1a-insensitive kal1a RNA (D). Dorsal is to the top, and ventral to the bottom. White arrows indicate defasciculated axon fibres within olfactory bulbs. Red arrows show disorganized olfactory sensory axons. OE, olfactory epithelium; ON, olfactory nerve; OB, olfactory bulbs. Scale bar = 50 μm.

Expression Data

Gene:	EGFP
Fish:	jt0012Tg jt0012Tg + MO2-anos1a
Knockdown Reagent:	MO2-anos1a
Anatomical Terms:	olfactory receptor cell olfactory receptor cell axon
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	jt0012Tg + MO2-anos1a
Knockdown Reagent:	MO2-anos1a
Observed In:	olfactory receptor cell axon
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Molecular and Cellular Endocrinology, 312(1-2), Yanicostas, C., Herbomel, E., Dipietromaria, A., and Soussi-Yanicostas, N., Anosmin-1a is required for fasciculation and terminal targeting of olfactory sensory neuron axons in the zebrafish olfactory system, 53-60, Copyright (2009) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.