FIGURE

Fig. 7

ID

ZDB-FIG-090804-74

Publication

Dodd et al., 2009 - The ENTH domain protein Clint1 is required for epidermal homeostasis in zebrafish

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Fig. 7

Impaired hemidesmosome formation in clint1 mutants. Transmission electron micrographs of transverse sections of wild-type (A-D) and clint1 mutant (A′-D′,E,F) zebrafish embryos staged at 4 dpf. The dashed boxed regions in A and A′ are magnified in B and B′, respectively. The solid boxed region in A is magnified in C. Arrowheads label hemidesmosomes (B), desmosomes (C,C′), tight junctions (D,D′), cellular fragmentation (A′,F) and condensed nuclei (E). Asterisks highlight absence of hemidesmosomes (B′) and detachment of epidermal cells (C′). N, nucleus; BL, basal lamina. Scale bars: 1 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	clint1a^{hi1520Tg/hi1520Tg} (AB)
Observed In:	apoptotic chromosome condensation epidermis epidermis hemidesmosome
Stage:	Day 4

Phenotype Detail

Acknowledgments

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