FIGURE

Fig. 2

ID
ZDB-FIG-090519-50
Publication
Sepich et al., 1994 - Autonomous expression of the nic1 acetylcholine receptor mutation in zebrafish muscle cells
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Fig. 2

AChRs fail to cluster on nic1 muscle cells contacted by wild-type motoneurons. (A) The axon of a fluorescein-dextran-labeled wild-type motoneuron (arrowhead) contacts several labeled wild-type (arrow) and unlabeled nic1 muscle fibers in a live embryo. (B) R-BTX-labeled AChR patches (arrow) appear only on wild-type muscle cells. Arrowhead indicates the location of the axonal varicosity (indicated in A) overlying a nic1 muscle fiber. We obtained the same result with three transplanted wild-type motoneurons innervating nic1 muscle cells. Trunk segment; 80 h; scale bar, 20 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 161, Sepich, D.S., Ho, R.K., and Westerfield, M., Autonomous expression of the nic1 acetylcholine receptor mutation in zebrafish muscle cells, 84-90, Copyright (1994) with permission from Elsevier. Full text @ Dev. Biol.