FIGURE

Fig. 4

ID

ZDB-FIG-090408-86

Publication

Rossi et al., 2009 - Transcriptional control of Rohon-Beard sensory neuron development at the neural plate border

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Fig. 4

prdm1a affects dlx3b and dlx4b expression unidirectionally at the NPB. A,B: dlx3b expression is decreased at the NPB in prdm1a mutant embryos (B) compared to WT embryos (A) at tail bud. C-F: Embryos injected with antisense oligonucleotide morpholino to prdm1a show a decrease in dlx4b at the NPB at tail bud (D) and an absence of HuC-positive RBs (F) at 2 somites compared to un-injected controls (C, E). Conversely, prdm1a expression at the NPB shows no change in dlx3b/4b morpholino-injected embryos [compare un-injected controls at 90% epiboly (G) and tail bud (I) to morphants (H,J)]. Lateral (A-D, G-J) or dorsal (E,F) views with anterior toward the top.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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