Fig. 1
- ID
- ZDB-FIG-081201-1
- Publication
- Esterberg et al., 2008 - Tailbud-derived Bmp4 drives proliferation and inhibits maturation of zebrafish chordamesoderm
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Expansion of the tailbud in Fstl1/2 morphant embryos. (A-T) Expression of the tailbud markers spt (A-D), bmp4 (E-H), PSMAD1/5/8 (I-L) and eve1 (M-P), and the posterior axial marker admp (Q-T) in six-somite embryos injected with control morpholino (A,E,I,M,Q), fstl1/2 morpholino (B,F,J,N,R), fstl2 mRNA (C,G,K,O,S), and fstl1/2 morpholino and fstl2 mRNA (D,H,L,P,T). (U) Levels of PSMAD1/5/8, but not PSMAD2, are increased in Fstl1/2 morphants beginning at late gastrulation. All views except E-L are dorsal views, with anterior towards the top. (E-L) Lateral views, with anterior towards the left. Brackets illustrate the expression domain observed in control embryos. Arrows indicate the tailbud. Insets in E-H are views of the tailbud. |
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Stage Range: | 75%-epiboly to 14-19 somites |