FIGURE

Fig. 8

ID

ZDB-FIG-070822-34

Publication

Yang et al., 2007 - Mutations in gfpt1 and skiv2l2 Cause Distinct Stage-Specific Defects in Larval Melanocyte Regeneration in Zebrafish

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Fig. 8

skiv2l2 Expression Is Ubiquitous during Embryogenesis and Then Restricted to Proliferation Zones at Larval Stages (A and B) skiv2l2 transcripts were detected as early as the four-cell stage by RNA ISH (A) and remained ubiquitously distributed in embryos throughout early embryogenesis (B) (12 hpf). (C and D) The expression of skiv2l2 becomes stronger in the central nervous system (arrowhead in [C]) (22 hpf) and is then restricted to pectoral fins, cranial neural crest (white arrow in [D]), the medial and posterior parts of the tectum, and cerebellum (black arrow in [D]), and ciliary marginal zone of the retina (arrowhead in [D]) at larval stages (D) (74 hpf). (E) This larval-stage expression pattern of skiv2l2 is nearly identical to the expression of pcna (68 hpf). (F) pcna expression is drastically reduced in julie^j24e1 mutants (68 hpf). Scale bars: in (A), 100 μm for (A–C); in (D), 100 μm for (D–F).

Expression Data

Genes:	mtrex pcna
Fish:	WT mtrex^j24e1/j24e1 (SJD/C32)
Anatomical Terms:	blastomere central nervous system cerebellum ciliary marginal zone optic tectum pectoral fin unspecified whole organism (all 8)
Stage Range:	4-cell to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mtrex^j24e1/j24e1 (SJD/C32)
Observed In:	cell population proliferation
Stage:	Pec-fin

Phenotype Detail

Acknowledgments

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