ZFIN ID: ZDB-FIG-070813-39
Miller et al., 2007 - mef2ca is required in cranial neural crest to effect Endothelin1 signaling in zebrafish. Developmental Biology   308(1):144-157 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Term:
Stage: Prim-15

Fig. 8 mef2ca activates dlx5a, dlx6a, and dlx4b but represses dlx3b. Lateral views of expression of dlx2a (A, B), dlx5a (C, D), dlx6a (E, F), dlx3b (G, H) and dlx4b (I, J) in wild-type (A, C, E, G, I) and mef2ca mutant (B, D, F, H, J) heads of 30 hpf zebrafish embryos. (A, B) mef2ca mutants have no detectable alteration in dlx2a expression, which is expressed throughout pharyngeal arch CNC. (C–F) Expression of both dlx5a and dlx6a, in ventral and intermediate CNC in wild-types, is reduced in mef2ca mutants. (G, H) dlx3b expression is ectopically expressed in dorsal arch CNC of mef2ca mutants (arrows). In G-H, first pharyngeal pouch is outlined. (I, J) In contrast, dlx4b expression, restricted to ventral arch CNC, is largely undetectable in mef2ca mutants. The first two arches are numbered. Scale bar: 50 μM.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
dlx2a WT control Prim-15 pharyngeal arch ISH
mef2cab1086/b1086 control Prim-15 pharyngeal arch ISH
dlx3b WT control Prim-15 pharyngeal arch ISH
mef2cab1086/b1086 control Prim-15 pharyngeal arch ISH
dlx4b WT control Prim-15 pharyngeal arch ISH
mef2cab1086/b1086 control Prim-15 pharyngeal arch ISH
dlx5a WT control Prim-15 pharyngeal arch ISH
mef2cab1086/b1086 control Prim-15 pharyngeal arch ISH
dlx6a WT control Prim-15 pharyngeal arch ISH
mef2cab1086/b1086 control Prim-15 pharyngeal arch ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
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Reprinted from Developmental Biology, 308(1), Miller, C.T., Swartz, M.E., Khuu, P.A., Walker, M.B., Eberhart, J.K., and Kimmel, C.B., mef2ca is required in cranial neural crest to effect Endothelin1 signaling in zebrafish, 144-157, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.