FIGURE

Fig. 1

ID

ZDB-FIG-070710-1

Publication

Chocron et al., 2007 - Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points

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Fig. 1

Laterality defects in laf/alk8 mutant embryos. (A–C) Wild-type sibling (A) and laf/alk8 mutant (B) embryo at 30 hpf stained for cmlc2 expression to reveal positioning of the heart and quantification of the results (C). (D–G) Wild-type sibling (D) and laf/alk8 mutant (E, F) embryos at 50 hpf stained for foxa3 expression to reveal the positioning of the liver (l), pancreas (p) and gut (g) and quantification of the results (G). (H–K) Wild-type sibling (H) and laf/alk8 mutant (I, J) embryos at 22 somite stage stained for lefty1 expression in the dorsal diencephalon and quantification of the results (K). All pictures are of dorsal views with anterior to the top (M, middle; L, left; R, right; B, bilateral; A, absent).

Expression Data

Genes:	foxa3 lft1 myl7
Fish:	acvr1l^{tm110b/tm110b} (TU) acvr1l^tm110b/+ (TU)
Anatomical Terms:	diencephalon gut heart tube liver pancreas
Stage Range:	20-25 somites to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	acvr1l^{tm110b/tm110b} (TU)
Observed In:	atrium diencephalon heart looping
Stage Range:	20-25 somites to Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 305(2), Chocron, S., Verhoeven, M.C., Rentzsch, F., Hammerschmidt, M., and Bakkers, J., Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points, 577-588, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.