FIGURE

Fig. 3

ID
ZDB-FIG-051123-3
Publication
Norton et al., 2005 - HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development
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Fig. 3

fgf10/dae mutant embryos have reduced expression of AER markers. Lateral views of wild-type (B,E,G,K,I,M,O,S,Q,U,W) and mutant fins (C,F,H,L,J,N,P,T,R,V,X), with anterior towards left. At 28 hpf, expression of fgf24 and bmp2b appears indistinguishable in wild-type and fgf10/dae (A,D). Expression of sp8 is weakly reduced in dae (H) but sp9 (L), dlx2a (P) and wnt3l (T) expression is strongly reduced in mutants. By 38 hpf, expression of all ridge markers analysed is reduced in fgf10/dae (C,F,J,N,R,V,X) when compared with siblings (B,E,I,M,Q,U,W).

Expression Data
Genes:
Fish:
Anatomical Terms:
Stage Range: Prim-5 to Prim-25

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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