CRISPR

CRISPR1-mbnl2

ID

ZDB-CRISPR-220418-3

Name

CRISPR1-mbnl2

Previous Names

None

Target

mbnl2 (1)

Sequence

5' - ATCGACACGAGCGACAACA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
b1360	mbnl2

Expression

Gene expression in Wild Types + CRISPR1-mbnl2

No data available

Phenotype

Phenotype resulting from CRISPR1-mbnl2

No data available

Phenotype of all Fish created by or utilizing CRISPR1-mbnl2

Phenotype	Fish	Conditions	Figures
swimming increased occurrence, abnormal	mbnl2^b1360/b1360	standard conditions	Fig. 2. from Hinman et al., 2021
whole organism decreased length, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 1. from Hinman et al., 2021
heart alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
skeletal muscle alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 3. , Fig. 5. from Hinman et al., 2021
intestine alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
cornea alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
swimming decreased occurrence, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 2. from Hinman et al., 2021
whole organism alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
brain alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
skeletal muscle alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl3^b1363/b1363	standard conditions	Fig. 5. from Hinman et al., 2021
whole organism alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
intestine alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
brain alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
heart alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
skeletal muscle alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. , Fig. 5. from Hinman et al., 2021
cornea alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
swimming decreased occurrence, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 2. from Hinman et al., 2021
whole organism alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
brain alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
intestine alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
whole organism decreased length, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 1. from Hinman et al., 2021

Citations