CRISPR

CRISPR4-esr1

ID

ZDB-CRISPR-180419-4

Name

CRISPR4-esr1

Previous Names

None

Target

Sequence

5' - GTCCTCTCAGCAGGCAGCCG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
uab118	esr1
uab119	esr1

Expression

Gene expression in Wild Types + CRISPR4-esr1

No data available

Phenotype

Phenotype resulting from CRISPR4-esr1

No data available

Phenotype of all Fish created by or utilizing CRISPR4-esr1

Phenotype	Fish	Conditions	Figures
whole organism dead, abnormal	esr1^{uab119/uab119} (AB)	chemical treatment by environment: 2,3,7,8-tetrachlorodibenzodioxine	Fig. 7 from Souder et al., 2019
heart looping process quality, abnormal	esr1^{uab119/uab119} (AB)	chemical treatment by environment: 2,3,7,8-tetrachlorodibenzodioxine	Fig. 7 from Souder et al., 2019
pericardium edematous, abnormal	esr1^{uab119/uab119} (AB)	chemical treatment by environment: 2,3,7,8-tetrachlorodibenzodioxine	Fig. 7 from Souder et al., 2019
heart contraction increased rate, abnormal	esr1^{uab118/uab118}; c262Tg/c262Tg	chemical treatment by environment: 17beta-estradiol	Fig. S5 from Romano et al., 2017
heart valve EGFP expression absent, abnormal	esr1^{uab118/uab118}; c262Tg/c262Tg	chemical treatment by environment: 17beta-estradiol	Fig. S2 from Romano et al., 2017
heart contraction increased rate, abnormal	esr1^{uab118/uab118}; c262Tg/c262Tg	chemical treatment by environment: 17beta-estradiol	Fig. 3 from Romano et al., 2017

Citations