Genomic Feature
mi605
- ID
- ZDB-ALT-200325-3
- Name
- mi605
- Synonyms
-
- D7 (1)
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one delins (1)
- Protocol
- embryos treated with
- Lab of Origin
- Cunming Duan Lab
- Current Source
- Other Pages
Notes
| Comment | Citation |
|---|---|
| Trpv6 mutant protein lacks the six transmembrane domains and the critical ion ... | Xin et al., 2019 |
Variants
- Variant Type
- Delins
- Variant Location
- Chr 16: 12312266 - 12312281 (GRCz11) (1) Details
- Nucleotide change
- CTCGTTGATGAGCTCC/GCTCGTGAT
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 9 bp inserted / 16 bp deleted (1)
- Transcript Consequence
- Frameshift (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
TACACTGCTGACCTTACAAACTCCACTTAACCCACCTTTAAATCCACCAATTCCAGTAAACCACTGGTTGCTAAACGTAACAGTATCCCACTTCAACAACATTTTGCAATACAACATGACCACAATATGGACATTATACCTAACAATTATTCTTTATTCCATGCATGTACCATATAGTAGCTAACAGAGTGTGACCATACGAACAATAGCTAAAAATGATTACCACAATAGAAGCATATGTCTCACCATAGTAAAACAGGCCTTCTCTTCTTTTGCGGAAGTACATGCCTGTGACTCTGGGTGTCGTCACATCAGCTCCTCTTTTTATCATCTCCCAGATTAAGTTAGGATTCTGATTAATCACAGCGATGTGAAGGGCTGTTAAACCTGTCAATCAGAGCACACTTGCTTAAGATTTTACAGTGTGAACAGTCATATTTAATTGTTTGAGGAAGTGTCTGTTTCTAATAATGACCATGGTAGAGTTCAGATGTCATGGG
CTCGTTGATGAGCTCC/GCTCGTGAT GGGGCTCCATTCATTAAAGCCACCGCTGCTTCAAAGTTATCATTCATCACAGCAACATGCAGAGCTGTCTCTCCAAGCTCACCTGCAACAAACACACACAATGTCAGAGACACATTTACAATCTGTATTTATCATTCAGTGCATTGTTAGATATTAAGACATTAAAGCAACGTTCTGTCATGAAACCGCCATGAAACGAAGGCTGTAAGTCCTATCCAGTTTGCTTCTAACCATATTGTTAAATAAGGCGCAGGTGAGCAGCCAATGGGCTTGCTTCTCAATATTTAAATATCTTGTATTATTTGGAATAGCAATCTACAGTACGTTTTTGGGATAGCTGTCTGAAAATTAAGTTAAAATAAGTGAAGATAATCCCTAAATTTAATCCTTTTGCTGATCTGCTCACTGTTTTAAGTAAGCACTCATACATTTAAATTCAGGCTCCATGTTTACAAGTTTCAGACTGATCTCACGAGGAAACGTAAGTATTTTACGTTTTG - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| trpv6mi605/mi605; mi602Tg | Complex | 3 figures  from Xin et al., 2019 | Fig. 3 supplemental 1 from Xin et al., 2019 | ||
| trpv6mi605/mi605; mi602Tg/mi602Tg | Complex | 2 figures from Xin et al., 2021 | |||
| trpv6mi605/+; mi602Tg | Complex | Figure 3 from Xin et al., 2019 | Fig. 3 supplemental 1 from Xin et al., 2019 |
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Supplemental Information
- Genotyping protocol
- None
- Xin, Y., Guan, J., Li, Y., Duan, C. (2021) Regulation of cell quiescence-proliferation balance by Ca2+-CaMKK-Akt signaling. Journal of Cell Science. 134(20):
- Xin, Y., Malick, A., Hu, M., Liu, C., Batah, H., Xu, H., Duan, C. (2019) Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6. eLIFE. 8:
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