Genomic Feature
nz15
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 7: 30352292 (GRCz11) (1) Details
- Nucleotide change
- G/T
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- C>A at position 174 (1)
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- Tyr>Stop at position 58 (1)
- Flanking Sequence
-
AATGATATAACATTATCCTCCAAACAGGTGTTTGTCCACCTCAGGGACAAATTAAATCCATTCATTCCGGATGAGTCTCAATGACTTCCCCAGTTGCACGTTCAGGGGGTCTCTATTTCCTGTATCCATTCTGGTTTTCCACACTTTCTGCCTGATTTACAGAGAGGAACTACAGCCTCTAGCTTGCTTAACCACATTAGACTGAACTACAGCCCCTTCCCTCCCTCTCTTTCAGTTCTGGATGCTTATTCATGCTGAGTGAAGGCTGAAAGTGAGAAGCACAATAGCGGCGCTGGACGACTAAATGTAGTCCAGCAGAGCAATTGTGCCAAACCTGTTTCTGGCAATGCTTTGACCAATTACCAAATACACACTCTGCTGACAAACACACTAGCATGCTAAGAAACCACACACGCGCGCACACACACACACACACACACACACAAACAGACCTTGTCGGATTCCTGGACATCACAGATCTTCTCTCCTGTGGCAGGGTT
G/T TACGTGTGGAAGACCTTGCCGCTCACAGAATCATGCCATTCATTATTAATAAAAATCTACAATGAGAGAAAGGAAAGATATTGTTTAGTTTTCACAACAGTTTTAAAGCAACAAGGTGGAAGTTAGGCAGAACTATCTCAGAATTGTAGCTTTGTGTTGTGGAAGGGTTGTCTGAATGTTCTGAACGAAAGTTCTTCCAGTGACATTAAATAAACATTCTGCTTTCTAATGTTCTCAAAATGTTACCACAAAATCATTTCAGCAATTCTTTGATAGAAGTGCTATAAGCAAGAAGACATAAAACTATATTAAAATTTGAAATGCTGAAATGAACAATGCAGCCAATTACAAAAACTTCTATACAAAAAAATATTTTTTATTCTTAATATACAGTGCAATACTGCAAAGAAGATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACATATATATATATATACATATATATATATT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| aldh1a2nz15/nz15 | Homozygous | ♀+/- ♂+/- | 2 figures from 2 publications | 2 figures from 2 publications | |
| aldh1a2nz15/nz15 (TU) | Homozygous | ♀+/- ♂+/- | 4 figures  from Wingert et al., 2011 | 4 figures from Wingert et al., 2011 | |
| aldh1a2i26/+; aldh1a2nz15/+ (TU) | Complex | 2 figures from Wingert et al., 2011 | Fig. 5 from Wingert et al., 2011 | ||
| aldh1a2nz15/nz15 + MO1-irx3b + MO2-irx3b (TU) | Complex | Fig. 7 from Wingert et al., 2011 | Fig. 7 from Wingert et al., 2011 |
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Supplemental Information
- Genotyping protocol
- None
- Cheng, C.N., Li, Y., Marra, A.N., Verdun, V., Wingert, R.A. (2014) Flat Mount Preparation for Observation and Analysis of Zebrafish Embryo Specimens Stained by Whole Mount In situ Hybridization. Journal of visualized experiments : JoVE. (89)
- Li, Y., Cheng, C.N., Verdun, V.A., and Wingert, R.A. (2014) Zebrafish nephrogenesis is regulated by interactions between retinoic acid, mecom, and Notch signaling. Developmental Biology. 386(1):111-122
- Miceli, R., Kroeger, P., Wingert, R. (2014) Molecular Mechanisms of Podocyte Development Revealed by Zebrafish Kidney Research. Cell & developmental biology. 3:353-7
- Wingert, R.A., and Davidson, A.J. (2011) Zebrafish nephrogenesis involves dynamic spatiotemporal expression changes in renal progenitors and essential signals from retinoic acid and irx3b. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(8):2011-2027
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