ZFIN Lab: de la Pompa Lab

ZFIN ID: ZDB-LAB-191119-1

de la Pompa Lab

PI/Director:	de la Pompa, José Luis
Contact Person:	de la Pompa, José Luis
Email:	jlpompa@cnic.es
URL:	http://www.cnic.es/en/desarrollo/intercelular/index.php
Address:	Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, 28029 Madrid
Country:	Spain
Phone:	+34-91-4531334
Fax:	+34-91-4531240
Line Designation:	cn

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 16 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Grego Bessa, Joaquín Jacob Post-Doc	Luna Zurita, Luis Post-Doc	Ferreira Oliveira, Vera Lúcia Research Staff
González Costa, Tamara Research Staff	Grivas, Dimitrios Research Staff	Macgrogan, Donal Research Staff
Piñeiro Sabarís, Rebeca Research Staff	Prados Pinto, Belen Research Staff	Salguero Jiménez, Alejandro Research Staff
Siguero Álvarez, Marcos Research Staff	Torregrosa Carrión, Rebeca Research Staff	Bou Pérez, Vanesa Technical Staff
Galicia Martín, Abel Technical Staff	García Espada, Vanessa Technical Staff	Lendínez González, Cristina Technical Staff
Méndez Peralta, Lucía Technical Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Torregrosa-Carrión, R., Piñeiro-Sabarís, R., Siguero-Álvarez, M., Grego-Bessa, J., Luna-Zurita, L., Fernandes, V.S., MacGrogan, D., Stainier, D.Y.R., de la Pompa, J.L. (2021) Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development. Science advances. 7:eabj5445

Grivas, D., González-Rajal, Á., de la Pompa, J.L. (2021) Midkine-a Regulates the Formation of a Fibrotic Scar During Zebrafish Heart Regeneration. Frontiers in cell and developmental biology. 9:669439

Andrés-Delgado, L., Galardi-Castilla, M., Münch, J., Peralta, M., Ernst, A., González-Rosa, J.M., Tessadori, F., Santamaría, L., Bakkers, J., Vermot, J., de la Pompa, J.L., Mercader, N. (2020) Notch and Bmp signaling pathways act coordinately during the formation of the proepicardium. Developmental Dynamics : an official publication of the American Association of Anatomists. 249(12):1455-1469

Grivas, D., González-Rajal, Á., Guerrero Rodríguez, C., Garcia, R., de la Pompa, J.L. (2020) Loss of Caveolin-1 and caveolae leads to increased cardiac cell stiffness and functional decline of the adult zebrafish heart. Scientific Reports. 10:12816

Torregrosa-Carrión, R., Luna-Zurita, L., García-Marqués, F., D'Amato, G., Piñeiro-Sabarís, R., Bonzón-Kulichenko, E., Vázquez, J., de la Pompa, J.L. (2019) NOTCH activation promotes valve formation by regulating the endocardial secretome. Molecular & cellular proteomics : MCP. 18(9):1782-1795

Andrés-Delgado, L., Ernst, A., Galardi-Castilla, M., Bazaga, D., Peralta, M., Münch, J., González-Rosa, J.M., Marques, I., Tessadori, F., de la Pompa, J.L., Vermot, J., Mercader, N. (2019) Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial cells. Development (Cambridge, England). 146(13):

MacGrogan, D., Münch, J., de la Pompa, J.L. (2018) Notch and interacting signalling pathways in cardiac development, disease, and regeneration. Nature reviews. Cardiology. 15:685-704

Del Monte-Nieto, G., Ramialison, M., Adam, A.A.S., Wu, B., Aharonov, A., D'Uva, G., Bourke, L.M., Pitulescu, M.E., Chen, H., de la Pompa, J.L., Shou, W., Adams, R.H., Harten, S.K., Tzahor, E., Zhou, B., Harvey, R.P. (2018) Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 557(7705):439-445

Münch, J., Grivas, D., González-Rajal, Á., Torregrosa-Carrión, R., de la Pompa, J.L. (2017) Notch signalling restricts inflammation and serpine1 expression in the dynamic endocardium of the regenerating zebrafish heart.. Development (Cambridge, England). 144(8):1425-1440

Münch, J., González-Rajal, A., and de la Pompa, J.L. (2013) Notch regulates blastema proliferation and prevents differentiation during adult zebrafish fin regeneration. Development (Cambridge, England). 140(7):1402-1411

Luxan, G., Casanova, J.C., Martinez-Poveda, B., Prados, B., D'Amato, G., Macgrogan, D., Gonzalez-Rajal, A., Dobarro, D., Torroja, C., Martinez, F., Izquierdo-García, J.L., Fernandez-Friera, L., Sabater-Molina, M., Kong, Y.Y., Pizarro, G., Ibañez, B., Medrano, C., García-Pavía, P., Gimeno, J.R., Monserrat, L., Jimenez-Borreguero, L.J., and de la Pompa, J.L. (2013) Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nature medicine. 19(2):193-201

Rodríguez, P., Higueras, M.A., González-Rajal, A., Alfranca, A., Fierro-Fernández, M., García-Fernández, R.A., Ruiz-Hidalgo, M.J., Monsalve, M., Rodríguez-Pascual, F., Redondo, J.M., de la Pompa, J.L., Laborda, J., and Lamas, S. (2012) The non-canonical NOTCH ligand DLK1 exhibits a novel vascular role as a strong inhibitor of angiogenesis. Cardiovascular research. 93(2):232-241

Del Monte, G., Grego-Bessa, J., González-Rajal, A., Bolós, V., and De La Pompa, J.L. (2007) Monitoring Notch1 activity in development: Evidence for a feedback regulatory loop. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(9):2594-2614

Timmerman, L.A., Grego-Bessa, J., Raya, A., Bertran, E., Perez-Pomares, J.M., Diez, J., Aranda, S., Palomo, S., McCormick, F., Izpisúa Belmonte, J.C., and De La Pompa, J.L. (2004) Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes & Development. 18(1):99-115