ZFIN Lab: Alsina Lab

ZFIN ID: ZDB-LAB-110119-1

Alsina Lab

PI/Director:	Alsina, Berta
Contact Person:	Sas, Miquel
Email:	miquel.sas@upf.edu
URL:	http://www.upf.edu/devbiol/projectes/Alsina_lab.html
Address:	Laboratory of Developmental Biology Universitat Pompeu Fabra-PRBB Dr. Aiguader 88, 08003 Barcelona, Spain
Country:	Spain
Phone:	+34 933160817
Fax:
Line Designation:	pfu

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

Neurogenesis and patterning mechanisms in the inner ear, sensory gene cis- regulatory elements.

LAB MEMBERS

Moreno, Alex Robert Post-Doc	Radosevic, Marija Graduate Student	Linares, Marta Technical Staff
Sas, Miquel Technical Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Bañón, A., Alsina, B. (2023) Pioneer statoacoustic neurons guide neuroblast behaviour during otic ganglion assembly. Development (Cambridge, England). 150(21):

Samper-Martín, B., Sarrias, A., Lázaro, B., Pérez-Montero, M., Rodríguez-Rodríguez, R., Ribeiro, M.P.C., Bañón, A., Wolfgeher, D., Jessen, H.J., Alsina, B., Clotet, J., Kron, S.J., Saiardi, A., Jiménez, J., Bru, S. (2021) Polyphosphate degradation by Nudt3-Zn²⁺ mediates oxidative stress response. Cell Reports. 37:110004

Taberner, L., Bañón, A., Alsina, B. (2020) Sensory Neuroblast Quiescence Depends on Vascular Cytoneme Contacts and Sensory Neuronal Differentiation Requires Initiation of Blood Flow. Cell Reports. 32:107903

Taberner, L., Bañón, A., Alsina, B. (2017) Anatomical map of the cranial vasculature and sensory ganglia. Journal of anatomy. 232(3):431-439

Hoijman, E., Fargas, L., Blader, P., Alsina, B. (2017) Pioneer neurog1 expressing cells ingress into the otic epithelium and instruct neuronal specification.. eLIFE. 6

Alsina, B., Whitfield, T.T. (2017) Sculpting the labyrinth: morphogenesis of the developing inner ear. Seminars in cell & developmental biology. 65:47-59

Rubbini, D., Robert-Moreno, À., Hoijman, E., Alsina, B. (2015) Retinoic Acid Signaling Mediates Hair Cell Regeneration by Repressing p27kip and sox2 in Supporting Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35:15752-66

Hoijman, E., Rubbini, D., Colombelli, J., Alsina, B. (2015) Mitotic cell rounding and epithelial thinning regulate lumen growth and shape. Nature communications. 6:7355

Iturbide, A., Pascual-Reguant, L., Fargas, L., Cebrià, J.P., Alsina, B., García de Herreros, A., Peiró, S. (2015) LOXL2 Oxidizes Methylated TAF10 and Controls TFIID-Dependent Genes during Neural Progenitor Differentiation. Molecular Cell. 58(5):755-66

Radosevic, M., Fargas, L., Alsina, B. (2014) The Role of her4 in Inner Ear Development and Its Relationship with Proneural Genes and Notch Signalling. PLoS One. 9:e109860

Mora, N., Almudi, I., Alsina, B., Corominas, M., and Serras, F. (2013) The Beta-amyloid protein precursor like (Appl) is a Ras1/MAPK regulated gene required for axonal targeting in Drosophila photoreceptor neurons. The Journal of cell biology. 126(1):53-59

Radosevic, M., Robert-Moreno, A., Coolen, M., Bally-Cuif, L., and Alsina, B. (2011) Her9 represses neurogenic fate downstream of Tbx1 and retinoic acid signaling in the inner ear. Development (Cambridge, England). 138(3):397-408

Robert-Moreno, A., Naranjo, S., de la Calle-Mustienes, E., Gomez-Skarmeta, J.L., and Alsina, B. (2010) Characterization of new otic enhancers of the pou3f4 gene reveal distinct signaling pathway regulation and spatio-temporal patterns. PLoS One. 5(12):e15907

Naranjo, S., Voesenek, K., de la Calle-Mustienes, E., Robert-Moreno, A., Kokotas, H., Grigoriadou, M., Economides, J., Van Camp, G., Hilgert, N., Moreno, F., Alsina, B., Petersen, M.B., Kremer, H., and Gómez-Skarmeta, J.L. (2010) Multiple enhancers located in a 1-Mb region upstream of POU3F4 promote expression during inner ear development and may be required for hearing. Human genetics. 128(4):411-419

Abello, G., and Alsina, B. (2007) Establishment of a proneural field in the inner ear. The International journal of developmental biology. 51(6-7):483-493

Aragon, F., Vazquez-Echeverria, C., Ulloa, E., Reber, M., Cereghini, S., Alsina, B., Giraldez, F., and Pujades, C. (2005) vHnf1 regulates specification of caudal rhombomere identity in the chick hindbrain. Developmental Dynamics : an official publication of the American Association of Anatomists. 234(3):567-576