ZFIN Lab: Hudspeth Lab

ZFIN ID: ZDB-LAB-011217-1

Hudspeth Lab

PI/Director:	Hudspeth, A.J. (Jim)
Contact Person:	Hudspeth, A.J. (Jim)
Email:	hudspaj@rockefeller.edu
URL:	http://www.rockefeller.edu/labheads/hudspeth/research_introduction.php
Address:	Laboratory of Sensory Neuroscience Box 314 The Rockefeller University 1230 York Avenue New York NY 10021-6399 USA
Country:	United States
Phone:	(212) 327-7351
Fax:	(212) 327-7352
Line Designation:	ru

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 12 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Asai, Yukako Post-Doc	Kappler, James A. Graduate Student	Starr, Catherine J. Graduate Student
Gleason, Michelle

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Jacobo, A., Dasgupta, A., Erzberger, A., Siletti, K., Hudspeth, A.J. (2019) Notch-Mediated Determination of Hair-Bundle Polarity in Mechanosensory Hair Cells of the Zebrafish Lateral Line. Current biology : CB. 29(21):3579-3587.e7

Dow, E., Jacobo, A., Hossain, S., Siletti, K., Hudspeth, A.J. (2018) Connectomics of the zebrafish's lateral-line neuromast reveals wiring and miswiring in a simple microcircuit. eLIFE. 7

Shah, P.K., Santella, A., Jacobo, A., Siletti, K., Hudspeth, A.J., Bao, Z. (2017) An In Toto Approach to Dissecting Cellular Interactions in Complex Tissues. Developmental Cell. 43:530-540.e4

Dow, E., Siletti, K., Hudspeth, A.J. (2015) Cellular projections from sensory hair cells form polarity-specific scaffolds during synaptogenesis. Genes & Development. 29:1087-94

Steiner, A.B., Kim, T., Cabot, V., Hudspeth, A.J. (2014) Dynamic gene expression by putative hair-cell progenitors during regeneration in the zebrafish lateral line. Proceedings of the National Academy of Sciences of the United States of America. 111:E1393-401

Mirkovic, I., Pylawka, S., and Hudspeth, A.J. (2012) Rearrangements between differentiating hair cells coordinate planar polarity and the establishment of mirror symmetry in lateral-line neuromasts. Biology Open. 1(5):498-505

McDermott, B.M., Asai, Y., Baucom, J.M., Jani, S.D., Castellanos, Y., Gomez, G., McClintock, J.M., and Hudspeth, A.J. (2010) Transgenic Labeling of Hair Cells in the Zebrafish Acousticolateralis System. Gene expression patterns : GEP. 10(2-3):113-118

Nagiel, A., Patel, S.H., Andor-Ardó, D., and Hudspeth, A.J. (2009) Activity-independent specification of synaptic targets in the posterior lateral line of the larval zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 106(51):21948-21953

Gleason, M.R., Nagiel, A., Jamet, S., Vologodskaia, M., Lopez-Schier, H., and Hudspeth, A.J. (2009) The transmembrane inner ear (Tmie) protein is essential for normal hearing and balance in the zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 106(50):21347-21352

Prober, D.A., Zimmerman, S., Myers, B.R., McDermott, B.M. Jr, Kim, S.H., Caron, S., Rihel, J., Solnica-Krezel, L., Julius, D., Hudspeth, A.J., and Schier, A.F. (2008) Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28(40):10102-10110

Nagiel, A., Andor-Ardó, D., and Hudspeth, A.J. (2008) Specificity of afferent synapses onto plane-polarized hair cells in the posterior lateral line of the zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28(34):8442-8453

McDermott, B.M., Baucom, J.M., and Hudspeth, A.J. (2007) Analysis and functional evaluation of the hair-cell transcriptome. Proceedings of the National Academy of Sciences of the United States of America. 104(28):11820-11825

Lopez-Schier, H., and Hudspeth, A.J. (2006) A two-step mechanism underlies the planar polarization of regenerating sensory hair cells. Proceedings of the National Academy of Sciences of the United States of America. 103(49):18615-18620

Asai, Y., Chan, D.K., Starr, C.J., Kappler, J.A., Kollmar, R., and Hudspeth, A.J. (2006) Mutation of the atrophin2 gene in the zebrafish disrupts signaling by fibroblast growth factor during development of the inner ear. Proceedings of the National Academy of Sciences of the United States of America. 103(24):9069-9074

Lopez-Schier, H., and Hudspeth, A.J. (2005) Supernumerary neuromasts in the posterior lateral line of zebrafish lacking peripheral glia. Proceedings of the National Academy of Sciences of the United States of America. 102(5):1496-1501

Luna, V.M., Wang, M., Ono, F., Gleason, M.R., Dallman, J.E., Mandel, G., and Brehm, P. (2004) Persistent electrical coupling and locomotory dysfunction in the zebrafish mutant shocked. Journal of neurophysiology. 92(4):2003-2009

Lopez-Schier, H., Starr, C.J., Kappler, J.A., Kollmar, R., and Hudspeth, A.J. (2004) Directional cell migration establishes the axes of planar polarity in the posterior lateral-line organ of the zebrafish. Developmental Cell. 7(3):401-412

Kappler, J.A., Starr, C.J., Chan, D.K., Kollmar, R., and Hudspeth, A.J. (2004) A nonsense mutation in the gene encoding a zebrafish myosin VI isoform causes defects in hair-cell mechanotransduction. Proceedings of the National Academy of Sciences of the United States of America. 101(35):13056-13061

Pataky, F., Pironkova, R., and Hudspeth, A.J. (2004) Radixin is a constituent of stereocilia in hair cells. Proceedings of the National Academy of Sciences of the United States of America. 101(8):2601-2606

Starr, C.J., Kappler, J.A., Chan, D.K., Kollmar, R., and Hudspeth, A.J. (2004) Mutation of the zebrafish choroideremia gene encoding Rab escort protein 1 devastates hair cells. Proceedings of the National Academy of Sciences of the United States of America. 101(8):2572-2577

Starr, C.J. (2003) A mutation in the zebrafish choroideremia gene causes hair-cell degeneration in the ear and lateral-line organ. Ph.D. Thesis. :154P

Kollmar, R., Nakamura, S.K., Kappler, J.A., and Hudspeth, A.J. (2001) Expression and phylogeny of claudins in vertebrate primordia. Proceedings of the National Academy of Sciences of the United States of America. 98(18):10196-10201

Liedtke, W., Dobrzynski, D., Kappler, J., Starr, C., Kollmar, R., Hudspeth, A.J., and Friedman, J.M. (2001) Screening for alterations in zebrafish thermoregulation and feeding behavior. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 15(5):A1103