- Title
-
Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
- Authors
- Walter, B., Hirsch, S., Kuhlburger, L., Stahl, A., Schnabel, L., Wisser, S., Haeusser, L.A., Tsiami, F., Plöger, S., Aghaallaei, N., Dick, A.M., Skokowa, J., Schmees, C., Templin, M., Schenke-Layland, K., Tatagiba, M., Nahnsen, S., Merk, D.J., Tabatabai, G.
- Source
- Full text @ J. Exp. Clin. Cancer Res.
Transcriptomic and proteomic profiling before and after ATRi treatment. |
CRISPR-Cas9 genome-wide knockout and activation screens identify novel combination partners for ATRi. |
Functionally-instructed combination therapies |
Combination of AZD6738 with Cisplatin or Fludarabine Phosphate show synergistic efficacy |