FIGURE SUMMARY
Title

Nuclease-Treated Stabilized Fermentation Product of Cetobacterium somerae Improves Growth, Non-specific Immunity, and Liver Health of Zebrafish (Danio rerio)

Authors
Xie, M., Hao, Q., Xia, R., Olsen, R.E., Ringø, E., Yang, Y., Zhang, Z., Ran, C., Zhou, Z.
Source
Full text @ Front Nutr
Fig. 1

Effects of XMX-1 and XMX-1 (N) diets on zebrafish survival, weight gain (%), and feed conversion ratio. (A) Initial body weight (g), (B) weight gain (percentage), (C) feed conversion ratio (FCR), and (D) survival rate with low dosage addition. (E) Initial body weight (g), (F) weight gain (percent), (G) feed conversion ratio (FCR), and (H) survival rate with high dosage addition. The means (SEMs) (n = 3) were used to represent the data. *p < 0.05 and **p < 0.01 comparison to the control group.
Fig. 2

Effects of XMX-1 and XMX-1 (N) diets on zebrafish body surface mucus immunity. (A) Lysozyme activity and (B) complement component 4 with low dosage addition. (C) Lysozyme activity and (D) total antioxidant capacity with high dosage addition. The means (SEMs) (n = 6) were used to represent the data. *p < 0.05 and ***p < 0.001 comparisons to the control group.
Fig. 3

Effects of XMX-1 and XMX-1 (N) diets on the expression of intestinal inflammation-related genes of zebrafish. (A) TNF-α, (B) IL-1β, (C) IL-10, and (D) TGF-β with low dosage addition. (E) TNF-α, (F) IL-1β, (G) IL-6, and (H) IL-10 with high dosage addition. The means (SEMs) (n = 6) were used to represent the data. *p < 0.05, **p < 0.01, and ***p < 0.001 comparison to the control group.
Fig. 4

Effects of XMX-1 and XMX-1 (N) diets on the gut microbiota of zebrafish. (A) Relative abundance; (B) principal coordinates analysis (PCoA) at phylum level of the gut microbiota with low dosage addition. (C) Relative abundance; (D) PCoA at phylum level of the gut microbiota with high dosage addition.
Fig. 5

Effects of XMX-1 and XMX-1 (N) diets on the expression of liver inflammation-related genes of zebrafish. (A) TNF-α, (B) IL-6, (C) IL-1β, and (D) IL-10 with low dosage addition. (E) TNF-α, (F) IL-6, (G) IL-1β, and (H) IL-10 with high dosage addition. The means (SEMs) (n = 6) were used to represent the data. *p < 0.05, **p < 0.01, and ***p < 0.001 comparison to the control group.
Fig. 6

Effects of XMX-1 and XMX-1 (N) diets on the expression of the content of TAG and hepatic lipid metabolism related genes of zebrafish liver. (A) TAG, (B) FAS, (C) ACC, (D) PPARα, (E) UCP2, (F) CPT1, and (G) PPARγ with low dosage addition. (H) TAG, (I) PPARγ, (J) UCP2, and (K) PGC1α with high dosage addition. The means (SEMs) (n = 6) were used to represent the data. *p < 0.05, **p < 0.01, and ***p < 0.001 comparison to the control group.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Nutr
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