FIGURE SUMMARY
- Title
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In vivo generation and regeneration of β cells in zebrafish
- Authors
- Yang, B., Covington, B.A., Chen, W.
- Source
- Full text @ Cell Regen (Lond)
Cell sources for in vivo generation of β cells in zebrafish. Cells in the extrapancreatic duct linking the pancreas to the gut (EPD) differentiate into endocrine progenitor cells that form the ventrally derived β cells in the principal islet. Centroacinar cells (CACs) are a specialized ductal pancreatic cell type that differentiates into progenitors of acinar, ductal, and endocrine cells. Under certain conditions, new β cells can be generated through transdifferentiation, neogenesis and proliferation |
Acknowledgments
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Full text @ Cell Regen (Lond)