- Title
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The Zebrafish (Danio rerio) Is a Relevant Model for Studying Sex-Specific Effects of 17β-Estradiol in the Adult Heart
- Authors
- Hein, S., Hassel, D., Kararigas, G.
- Source
- Full text @ Int. J. Mol. Sci.
Study design. Male and female zebrafish (4–6 months old) were treated with vehicle (control, CON) or 17β-estradiol (E2, 0.1 μM). Cardiac function was assessed by echocardiography at 0, 4, 7 and 14 days after treatment initiation ( |
Echocardiographic analysis of male and female zebrafish treated with or without E2. ( |
Gene expression analysis of estrogen receptors. ( |