FIGURE SUMMARY
Title

Non-Syndromic Cleft Lip with or without Cleft Palate: Genome-Wide Association Study in Europeans Identifies a Suggestive Risk Locus at 16p12.1 and Supports SH3PXD2A as a Clefting Susceptibility Gene

Authors
van Rooij, I.A., Ludwig, K.U., Welzenbach, J., Ishorst, N., Thonissen, M., Galesloot, T.E., Ongkosuwito, E., Bergé, S.J., Aldhorae, K., Rojas-Martinez, A., Kiemeney, L.A., Vermeesch, J.R., Brunner, H., Roeleveld, N., Devriendt, K., Dormaar, T., Hens, G., Knapp, M., Carels, C., Mangold, E.
Source
Full text @ Genes (Basel)
Figure 1

Regional association plot for a novel suggestive non-syndromic cleft lip with or without cleft palate (nsCL/P) locus on chromosome 16p12.1. Plotted SNVs include both genotyped and imputed variants.
Figure 2

Regional association plot for the candidate gene SH3PXD2A.
Figure 3

An unreported suggestive locus at chromosome 12q23.1 (a) Regional association plot showing a genome-wide significant marker upstream of the anoctamin 4 (ANO4) gene. It is of note that in our dataset, there were no SNVs in LD with the lead SNV rs73145631. (b) Regional association plot for the ANO4 gene.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Genes (Basel)
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.