Diverse effects of the microbiota on innate immune development and function in zebrafish. Colonization of germ-free zebrafish larvae with microbiota stimulates inflammatory gene expression (detected in specific tissues and whole larvae), neutrophil behavior and activity, neutrophil abundance in homeostasis, and neutrophil mobilization to injury. Boxes indicate different tissue-specific phenotypes that are known to be (black text) or are possibly (gray text) affected by microbiota.