FIGURE SUMMARY
Title

In vivo targeted single-nucleotide editing in zebrafish

Authors
Tanaka, S., Yoshioka, S., Nishida, K., Hosokawa, H., Kakizuka, A., Maegawa, S.
Source
Full text @ Sci. Rep.
Fig. 5

The Target-AID system can generate nucleotide substitution mutants. Phenotypic representation of (A, lateral view) a wild-type embryo and (B, lateral view) a chdc.232C>T/c.232C>T F2 embryo at 24 hpf. The open arrow and open arrowhead indicate a smaller head and expanded blood islands, respectively. Phenotypic representation of (C, lateral view), (E, ventral view) a wild-type embryo and (D, lateral view), (F, ventral view) an oepc.178C>T/c.178C>T F2 embryo at 27 hpf. The arrowhead indicates a single eye in each respective panel. (G,H) Expression pattern of gsc in (G, lateral view) a wild-type embryo and (H, lateral view) an oepc.178C>T/c.178C>T F2 embryo at the shield stage. (I,J) Expression pattern of hgg1 in (I, dorsal view) a wild-type embryo and (J, dorsal view) an oepc.178C>T/c.178C>T F2 embryo at the tailbud stage. Scale bars represent 100 μm.

EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Shield to Bud
PHENOTYPE:
Fish:
Observed In:
Stage Range: Shield to Prim-5
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.
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