FIGURE SUMMARY
Title

Enhancing Understanding of the Visual Cycle by Applying CRISPR/Cas9 Gene Editing in Zebrafish

Authors
Ward, R., Sundaramurthi, H., Di Giacomo, V., Kennedy, B.N.
Source
Full text @ Front Cell Dev Biol
Figure 1

Reactions involved in chromophore regeneration in rod and cone photoreceptors. Rod pigment regeneration is limited to the canonical pathway where RPE65 isomerises 11-cis-RAL from RE. Isomerization occurs independently of RPE65 in the cone specific pathway, involving the Müller glia. CRALBP is thought to be the primary 11-cis retinoid carrier in both pathways.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol
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