FIGURE SUMMARY
Title

Evolutionary and Expression Analyses Show Co-option of khdrbs Genes for Origin of Vertebrate Brain.

Authors
Wang, S., Yang, Q., Wang, Z., Feng, S., Li, H., Ji, D., Zhang, S.
Source
Full text @ Front Genet

Gene expression patterns of zebrafish khdrbs1a and khdrbs1b genes during early development detected by WISH. Stages of embryonic development: 0.45 hpf (A,A′), 3 hpf (B,B′), 6 hpf (C,C′), 10 hpf (D,D′), 14 hpf (E,E′), 24 hpf (F–I, F′–I′), 48 hpf (J–M, J′–M′), and 72 hpf (N–Q, N′–Q′). Expression sites are labeled with abbreviation as follows. cf, caudal fin; e, eye; gp, gonad primordium; hb, hindbrain; lln, lateral line neuromast; llp, lateral line primordium; mb, midbrain; ov, otic vesicle; pa, pharyngeal arch; pd, pronephric ducts; pt, pectoral fin; sp, spinal cord.

Gene expression domains of zebrafish khdrbs1a and khdrbs1b genes in brain detected by WISH and cryosection. Transverse sections of brain structures: telencephalon (E,I,E′,I′), diencephalon (F,J,F′,J′), midbrain (G,K,G′,K′) and hindbrain (C,D,H,L,C′,D′,H′,L′). Brain structure of zebrafish at 24 hpf (A,B,A′,B′). Straight lines, representing slice positions, are marked by English letters corresponding to the section images. Expression sites are labeled with abbreviation as follows. lln, lateral line neuromast.

EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Term:
Stage: Prim-5

Gene expression domains of zebrafish khdrbs1a gene in pronephric ducts detected by WISH and cryosection at 48 hpf. Straight lines represent slice positions (A,B). Transverse sections of zebrafish pronephric ducts at 48 hpf (C–E). Expression sites are labeled with abbreviation as follows. pd, pronephric ducts.

EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: Long-pec

Gene expression patterns of zebrafish khdrbs2 and khdrbs3 genes during early development detected by WISH. Stages of embryonic development: 0.45 hpf (A,A′), 3 hpf (B,B′), 6 hpf (C,C′), 10 hpf (D,D′), 14 hpf (E,E′), 24 hpf (F,I,L,F′,I′,L′), 48 hpf (G,J,M,G′,J′,M′), and 72 hpf (H,K,N,H′,K′,N′). Expression sites are labeled with abbreviation as follows. di, diencephalon; ep, epiphysis; hb, hindbrain; hr, hind rhombomeres; hy, hypothalamus; mb, midbrain; re, retina; sp, spinal cord; tec, tectum; teg, tegmentum; tel, telencephalon.

Gene expression domains of zebrafish khdrbs2 and khdrbs3 genes in brain detected by WISH and cryosection. Transverse sections of brain structures: telencephalon (A,E,I,A′,E′,I′), diencephalon (B,F,J,B′,F′,J′), midbrain (C,G,K,C′,G′,K′), and hindbrain (D,H,L,D′,H′,L′). Straight lines, representing slice positions, are marked by English letters corresponding to the section images. Expression sites are labeled with abbreviation as follows. ep, epiphysis; hy, hypothalamus; tec, tectum; teg, tegmentum; tel, telencephalon.

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Embryos hybridized with khdrbs1a, khdrbs1b, khdrbs2 and khdrbs3 sense riboprobes as control by WISH. Stages of embryonic development: 24 hpf (A, D, G, J), 48 hpf (B, E, H, K) and 72 hpf (C, F, I, L).

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Genet