CRISPR

CRISPR2-nrg1

ID

ZDB-CRISPR-180702-1

Name

CRISPR2-nrg1

Previous Names

None

Target

nrg1 (1)

Sequence

5' - CTCCCTCGGCCAAGACATCC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
nc26	nrg1
nc27	nrg1

Expression

Gene expression in Wild Types + CRISPR2-nrg1

No data available

Phenotype

Phenotype resulting from CRISPR2-nrg1

No data available

Phenotype of all Fish created by or utilizing CRISPR2-nrg1

Phenotype	Fish	Conditions	Figures
cardiac ventricle axonogenesis involved in innervation process quality, abnormal	nrg1^nc26/nc26	standard conditions	Fig. 4 from Brown et al., 2017
cardiac ventricle axon decreased length, abnormal	nrg1^nc26/nc26	standard conditions	Fig. 4 from Brown et al., 2017
whole organism decreased length, abnormal	nrg1^nc26/nc26	standard conditions	Fig. 2 from Brown et al., 2017
heart contraction increased variability of rate, abnormal	nrg1^nc26/nc26	standard conditions	Fig. 2 from Brown et al., 2017
whole organism decreased velocity, abnormal	nrg1^nc26/nc26	standard conditions	Fig. 2 from Brown et al., 2017
whole organism decreased life span, abnormal	nrg1^nc26/nc26	standard conditions	Fig. 2 from Brown et al., 2017
neuromast increased amount, abnormal	nrg1^nc26/nc26	standard conditions	Fig. 1 from Brown et al., 2017
whole organism decreased weight, abnormal	nrg1^nc26/nc26	standard conditions	Fig. 2 from Brown et al., 2017
whole organism swimming process quality, abnormal	nrg1^nc26/nc26	standard conditions	Fig. 2 from Brown et al., 2017
atrium axonogenesis involved in innervation disrupted, abnormal	nrg1^nc26/nc26	standard conditions	Fig. 4 from Brown et al., 2017
neuromast increased amount, abnormal	nrg1^nc27/nc27	standard conditions	Fig. S1 from Brown et al., 2017
myocardium nucleus decreased amount, abnormal	nrg1^nc26/nc26; f2Tg; s883Tg	standard conditions	Fig. 3 from Brown et al., 2017
myocardium decreased mass density, abnormal	nrg1^nc26/nc26; s883Tg	standard conditions	Fig. 3 from Brown et al., 2017
heart trabecula formation process quality, abnormal	nrg1^nc26/nc26; s883Tg	chemical treatment by environment: PD 168393	Fig. 1 from Brown et al., 2017

Citations