FIGURE SUMMARY
Title

Clusters of circulating tumor cells traverse capillary-sized vessels

Authors
Au, S.H., Storey, B.D., Moore, J.C., Tang, Q., Chen, Y.L., Javaid, S., Sarioglu, A.F., Sullivan, R., Madden, M.W., O'Keefe, R., Haber, D.A., Maheswaran, S., Langenau, D.M., Stott, S.L., Toner, M.
Source
Full text @ Proc. Natl. Acad. Sci. USA
Fig. S8

(A) Sagittal view of 3-d postfertilization Tg(kdrl:mCherry) transgenic zebrafish before transplantation. Arrows indicates where sharp “U turn” of blood occurs. (Scale bar: 250 µm.) (B) Xenotransplanted GFP-tagged Brx-50 cultured CTC cluster and singlet (green) occluding at the caudal end of the zebrafish where the dorsal aorta (DA) terminates and the caudal vein (CV) begins. (Scale bar: 50 µm.)

Fig. S9

(A) Sagittal view of head of 3-d postfertilization Tg(kdrl:mCherry) transgenic zebrafish showing transplanted human CTC cluster (white arrow) transiting through mandibular arch. (B) Close-up image of same transplanted CTC cluster (white arrow) showing displacement of cluster over time. Photomicrographs were captured less than 10 min apart. (Scale bar: 50 µm.)

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA
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