FIGURE SUMMARY
- Title
-
A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos
- Authors
- Bliman, D., Nilsson, J.R., Kettunen, P., Andréasson, J., Grøtli, M.
- Source
- Full text @ Sci. Rep.
Ret inhibition during development prevents motoneuron extension and axonal pathfinding in the zebrafish. (a) Picture showing the area of confocal imaging (red square) (b) Confocal image stacks of tg(olig2:dsRed) fish showing motoneuron axons after treatment with 6 and 1. Triangles mark stalling (white) and erroneous (yellow) axons. Scale bars: 20 µm. (c) Quantification of axonal phenotypes in the different treatments. n = number of axonal processes quantified. |
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Full text @ Sci. Rep.