FIGURE SUMMARY
- Title
-
Dioxin induction of transgenerational inheritance of disease in zebrafish
- Authors
- Baker, T.R., King-Heiden, T.C., Peterson, R.E., Heideman, W.
- Source
- Full text @ Mol. Cell. Endocrinol.
Transgenerational Effects of a Chemical Exposure in "Unexposed Offspring": F3 Generation Rodent is Equivalent to F2 Generation Zebrafish Comparison of the experimental design of a transgenerational study in the laboratory rodent and zebrafish. In the rodent model, in utero exposure to a chemical leads to direct exposure of the F0, F1 and F2 generations and the F3 generation is not exposed. In the zebrafish model, juvenile developmental exposure leads to direct exposure of the F0 and F1 generations to the chemical and the F2 generation is not exposed. |
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Reprinted from Molecular and Cellular Endocrinology, 398(1-2), Baker, T.R., King-Heiden, T.C., Peterson, R.E., Heideman, W., Dioxin induction of transgenerational inheritance of disease in zebrafish, 36-41, Copyright (2014) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.