GFP in zebrafish lens driven by the Ci-βγcry 275 bp construct (designated WT) and mutant binding site constructs. (A, B) Wild-type (WT) 275 bp constructs in two lines showing the whole fish. The lens is shown, as is the hindbrain (hb). (C, E) Wild-type (WT) 275 bp constructs in three separate lines, showing just the eye with the lens circled in C as a reference. (F)–(N) Lines with constructs with mutant (m) binding motifs as in Fig. 2C; mCDX1 (first Cdx motif mutated, 2 lines). mCDX2 (both Cdx motifs mutated, 2 lines). mCREB (CREB motif mutated, 2 lines). mFOX (Fox motif mutated, 1 line). mSOX (Sox motif mutated, 2 lines).